Lithium toxicity: A case report



lithium , neurotoxicity, theraupetic drug index, toxicity


Lithium is a commonly used drug for bipolar disorders and requires therapeutic dose monitoring due to its narrow therapeutic index. Acute lithium toxicity frequently occurs due to intentional intake of an excessive amount or due to its interaction with various medicines and medical conditions which alter its absorption or excretion. It may present primarily with neurological and gastrointestinal symptoms. We report a case of lithium toxicity in a patient with bipolar disorder probably due to dehydration and decreased intake of food and fluids. Frequent monitoring of serum lithium level while maintaining hydration and electrolyte balance successfully treated lithium toxicity.


Author Biographies

Ujjawal Paudel, Jibjibe Primary Health Care Center, Kalika-5, Rasuwa

Medical Officer

Gajendra Bham, Badegaun Primary Health Care Center, Lalitpur, Nepal

Medical Officer

Prashant Raj Bhatt, Palung Primary Health Care Center, Makwanpur

Medical Officer

Pradeep Ghimire, Patan Academy of Health Sciences, Lalitpur

Medical Officer

Aastha Parajuli, Kathmandu University Hospital, Dhulikhel

Medical Officer

Dipesh Upreti, Patan Academy of Health Sciences, Lalitpur