Extra intestinal manifestation of Crohn’s disease in a university teaching hospital, Nepal


  • Yuba Raj Sharma Patan Academy of Health Sciences


Introductions: Crohn’s disease relatively uncommon gastrointestinal
disease in Asia pacific region. There is increasing reports of this disease in the
region. Aim of this study was analyze the demographics and extraintestinal
manifestation of Crohn’s disease in tertiary care hospital setup in Nepal.

Methods: This was a retrospective study of patients with Chron’s disease
seen in gastroenterology unit of Patan Hospital from 2009 to 2014. Case
records were analyzed for age, gender, geography and extra intestinal

Results: Eighteen patients with Crohn’s disease were identified, 13 male
and five female. Age ranged from 14 to 70 years, with peak during 21-30
years. There were seven (39%) patients with extra intestinal manifestations
of arthritis, aphthous ulcer in oral cavity, erythema nodosum and episcleritis
in descending order.

Conclusions: Threre were 18 cases in five years from in our tertiary care
hospital and seven patients had extra intestinal presentation mainly arthritis
and oral aphthous ulcer. Clinicians in Asian region need to be vigilant of
Chron’s, once thought be the disease of developed countries.

Keywords: crohn’s disease, extra intestinal manifestation, inflammatory
bowel disease