Hepatitis B and HIV in Children and Pregnant Ladies at Patan Hospital
Introductions: The primary objective of this study was to find the prevalenceÂ of Hepatitis B and HIV infections in children and pregnant ladies visiting PatanÂ Hospital. The secondary objective wasto investigate how these individuals mayÂ have got infected, the clinical presentation and outcome.
Methods: Laboratory records of all individuals tested for Hepatitis B and HIVÂ between 2006 July to 2011 Aug were included. The charts were reviewed forÂ history and clinical findings
Results: Out of 44,958 individuals who were tested, 229 were positive. TheÂ prevalence of HIV was 0.2% and HBV 0.3% and both was 0.01% (5). The numbersÂ of children under age of 15 and of pregnant ladies were 13 and 32 respectively.Â Risk factors identified in 40 adult patients were: intravenous drug use, multipleÂ sex partners, working abroad and long distance drivers. Twenty-seven patientsÂ died, all with HIV. Of the 32 pregnant ladies 31 were discovered by routineÂ testing. All the babies born were healthy. Fever, cough and breathing difficultyÂ were the most common presenting features. Ten were treated for pneumoniaÂ and 3 for TB. Parents of 5 HIV-infected infants also had the same infectionÂ themselves. There was no death among children.
Conclusions: The prevalence of HBV and HIV was low. HBV was a â€˜hiddenâ€™
infection, discovered on routine testing of asymptomatic pregnant ladies.
Almost all children got these infections through vertical transmission.
Keywords: HVB, HIV, infection, seroprevalence